CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7718
Family Name Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole 63 family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00382615 Functional Category Bioactive with Natural Product
Superfamily Protease and Prothrombin Binder Superfamily
Class Class 2082

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-2-(1,3-b... 1 1
Prothrombin inhibitor (2S)-N-[(4-carbamimidoyl-1,3-thiazol-2-y... 3 2
Protease and Capsid scaffolding protein inhibitor AC1LAC7K family 2 5
Prothrombin inhibitor methyl 2-[(2S)-5-(diaminomethylideneamin... 4 2
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Prolyl endopeptidase inhibitor 1,3-benzothiazol-2-yl-[(2S)-1-[... 2 1
Capsid scaffolding protein inhibitor AC1LAC7W family 2 2
Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-4-(5-chloro-2-fl... 2 3
Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-N-[4-[6-(2-metho... 5 0
Luciferin 4-monooxygenase and Ras-related protein Rab-9A inhib... 2 1
Protein-cysteine N-palmitoyltransferase porcupine inhibitor N-... 4 1
Granzyme B inhibitor CHEMBL436855 family 2 2


External ID

Functional Category

Molecule Name

CFAMM00382613 CHEMBL176660 Bioactive 2-ketobenzothiazole 64
CFAMM00382616 CHEMBL404043 Bioactive (2S)-N-[(2S)-5-(diaminomethylideneamino)-1-(6-methoxy-1,3-benzothiazol-2-yl)-1-oxopentan-2-yl]-1-[(2R)-2-(methylamino)-3-phenylpropanoyl]pyrrolidine-2-carboxamide
CFAMM00382615 CHEMBL176031 Bioactive 2-ketobenzothiazole 63

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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