CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7722
Family Name Cannabinoid receptor 1 ligand 5-cyano-1-[(3,5-dichlorophenyl)methyl]-N-(3-hydroxy-2,2-dimethylpropyl)indole-2-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00382656 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Translocator protein Binder Superfamily
Class Class 929

Cousin Family NamesSeedsMembers
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Reverse transcriptase Inhibitor IDX899 Family 2 118
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Coagulation factor X and Prothrombin inhibitor N,1-bis[(3-carb... 1 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family 22 0
Glycogen phosphorylase, liver form inhibitor 2-[(1R,2R)-2-[(5-... 3 2


External ID

Functional Category

Molecule Name

CFAMM00382656 CHEMBL1760648 Bioactive 5-cyano-1-[(3,5-dichlorophenyl)methyl]-N-(3-hydroxy-2,2-dimethylpropyl)indole-2-carboxamide
CFAMM00382655 CHEMBL1760653 Bioactive 1-[(5-chloro-2-methylphenyl)methyl]-5-cyano-N-(3-hydroxy-2,2-dimethylpropyl)indole-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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