CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7746
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear receptor subfamily 1 group I member 2 ligand AGN-PC-0A9UI7 family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00382787 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear receptor subfamily 1 group I member 2 Binder Superfamily
Class Class 795

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 37
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 31 11
Glucocorticoid receptor ligand (2R)-1,1,1-trifluoro-4-(2-metho... 2 5
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 2 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 8 17
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (4Z)-... 1 0
Corticotropin-releasing factor receptor 1 ligand AGN-PC-005GB4... 6 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 5 9
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
ALK tyrosine kinase receptor and Nucleophosmin ligand N-[2-met... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
ALK tyrosine kinase receptor and Nucleophosmin ligand N-[2-met... 8 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 2
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 25 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand 1-... 8 6
Metabotropic glutamate receptor 2 ligand 8-chloro-3-(cycloprop... 6 2
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 12 2
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 5 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Type-1 angiotensin II receptor ligand AGN-PC-00FH82 family 1 1
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 4 0
Oxytocin receptor ligand AGN-PC-07C71T family 3 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor AGN-PC... 2 0
Acyl-CoA desaturase 1 inhibitor Pyridazine, 3-[4-(2-ethylpheno... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382788 CHEMBL1760806 Bioactive AGN-PC-0A9SM5
CFAMM00382787 CHEMBL1760803 Bioactive AGN-PC-0A9UI7

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27047 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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