CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7753
Family Name Cannabinoid receptor 2 ligand AGN-PC-0A9SMV family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00382809 Functional Category Bioactive
Superfamily Glucokinase and Cannabinoid receptor 2 Binder Superfamily
Class Class 144

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Reverse transcriptase Inhibitor Nevirapine Family 23 640
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Prothrombin Inhibitor Dabigatran Family 7 182
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
Translocator protein Inhibitor Emapunil Family 7 89
JAK Inhibitor Momelotinib Family 33 83
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... 2 7
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
Platelet-activating factor receptor ligand 5-methyl-2-[4-(2-me... 1 2
Transient receptor potential cation channel subfamily V member... 1 4
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
Adenosine receptor A2a ligand SureCN14156209 family 3 2
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-09M45... 8 1
Cell division cycle 7-related protein kinase inhibitor pyrrolo... 4 10
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Prelamin-A/C and Lethal(3)malignant brain tumor-like protein 1... 1 1
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 3
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Metabotropic glutamate receptor 5 ligand SureCN3866791 family 2 10
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Histamine H3 receptor ligand SureCN2878688 family 8 1
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Rho-associated protein kinase 2 and Rho-associated protein kin... 4 9
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
3-phosphoinositide-dependent protein kinase 1 and RAC-alpha se... 10 4
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor 6-[(3... 10 0
Aurora kinase B and Cyclin-dependent kinase 1 inhibitor 7-cycl... 3 16
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 3 4
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 1 1
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 6 0
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... 5 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... 5 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 1 0
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 1
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 10 4
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 4 0
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
Glycogen synthase kinase-3 beta inhibitor GSK-3beta Inhibitor ... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 22
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
Egl nine homolog 1 inhibitor 2-[(1,6-diphenylimidazo[4,5-c]pyr... 1 5
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Histamine H1 receptor ligand AGN-PC-005UAG family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382809 CHEMBL1760936 Bioactive AGN-PC-0A9SMV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48708 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543