CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7760
Family Name Melanin-concentrating hormone receptor 1 ligand SureCN3334191 family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00382828 Functional Category Bioactive
Superfamily Histamine H1 receptor Ligand Mizolastine Superfamily
Class Class 667

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Toll-like receptor 7 Ligand Imiquimod Family 3 237
Amiloride-sensitive sodium channel subunit alpha Ligand Triamt... 8 98
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Histamine H1 receptor Ligand Mizolastine Family 14 603
Prothrombin Inhibitor Dabigatran Family 7 182
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 5 129
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Transient receptor potential cation channel subfamily V member... 15 457
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
Translocator protein Inhibitor Emapunil Family 7 89
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Aurora kinase B and Aurora kinase A Inhibitor PF-03814735 Family 2 12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
HCV NS4B protein Inhibitor Clemizole Family 2 43
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
BIBT986 family 7 96
IPI-145 family 2 4
SB989 family 17 91
GDC-0349 family 44 77
JAK Inhibitor Momelotinib Family 33 83
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 55
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
Tryptase Inhibitor Babim Family 12 90
D(4) dopamine receptor Ligand L-745,870 Family 30 205
5-hydroxytryptamine receptor 2B Ligand MT-500 Family 8 39
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... 2 7
Histamine H3 receptor Ligand SCH79687 Family 11 29
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Vascular endothelial growth factor receptor 2 Ligand 6-(1h-ben... 2 5
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Peptide deformylase, mitochondrial Inhibitor 5-phenethyl-quina... 5 14
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Fatty-acid amide hydrolase 1 Inhibitor JNJ-1661010 Family 3 14
Histamine H4 receptor Ligand A-943931 Family 14 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand N-(9h-... 5 2
Type-2 angiotensin II receptor Ligand L-158282 Family 24 58
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 8
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Prothrombin inhibitor SureCN5854779 family 4 9
Prothrombin inhibitor SureCN5856722 family 3 16
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 1 4
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 9
Insulin receptor and Tyrosine-protein kinase Lck ligand AGN-PC... 1 1
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
Histone deacetylase 1 and Histone deacetylase 8 inhibitor (E)-... 3 0
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 13 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 2 21
Platelet-activating factor receptor ligand AGN-PC-0750SP family 4 0
Platelet-activating factor receptor ligand 8-bromo-2-[4-(2-met... 2 2
Histamine H4 receptor ligand SureCN602132 family 1 8
Neuronal acetylcholine receptor subunit alpha-7 ligand 2-(4-cy... 1 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Adenosine receptor A2a ligand AGN-PC-01LVXW family 2 25
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Neuropeptide Y receptor type 5 ligand 8-[6-(4-fluorophenyl)-1H... 2 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 27
Vascular endothelial growth factor receptor 2 and Mitogen-acti... 2 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Glucosylceramidase and Alpha-galactosidase A inhibitor AC1NNEG... 4 5
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 3
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Nociceptin receptor and Kappa-type opioid receptor ligand 1-[1... 4 4
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Coagulation factor X and Trypsin-1 inhibitor 1-(3-carbamimidoy... 4 1
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... 4 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Insulin-like growth factor 1 receptor ligand AGN-PC-09QGLU family 3 1
Bile acid receptor and Potassium voltage-gated channel subfami... 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 18
Lysosomal Pro-X carboxypeptidase inhibitor N-[(1S)-1-(5,6-dich... 3 21
Corticotropin-releasing factor receptor 1 ligand SureCN6301726... 4 1
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 5 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 1
Signal transducer and activator of transcription 6 inhibitor A... 3 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 4 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 0
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
C-C chemokine receptor type 5 ligand [4-[2-[3-(2-ethylbenzimid... 5 12
Cannabinoid receptor 1 ligand SureCN675796 family 5 1
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... 2 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Sonic hedgehog protein and Smoothened homolog inhibitor N-(4,4... 2 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Histamine H3 receptor ligand SureCN2878688 family 8 1
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 11 0
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
Histamine H1 receptor and Histamine H4 receptor ligand [4-[2-[... 1 1
Histamine H4 receptor and Histamine H3 receptor ligand (E)-[(3... 4 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Histamine H1 receptor and Potassium voltage-gated channel subf... 1 2
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 2
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 2 2
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[(3S)-3-[(4... 2 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Cell division cycle 7-related protein kinase and Protein DBF4 ... 15 7
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... 2 13
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 3 4
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 1 0
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 0
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... 2 2
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... 6 12
Melanin-concentrating hormone receptor 1 ligand 6-(4-chlorophe... 8 1
Fibroblast growth factor receptor 1 and Vascular endothelial g... 5 0
Renin inhibitor AGN-PC-073MLF family 7 6
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 2
Calcitonin gene-related peptide type 1 receptor ligand SureCN1... 1 4
Succinate receptor 1 ligand N-[[4-(3-methylphenyl)phenyl]methy... 2 14
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 1
Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... 6 2
Melanin-concentrating hormone receptor 1 ligand 3-[(1R,3R,6S)-... 2 4
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... 1 0
Type-1 angiotensin II receptor and Type-1A angiotensin II rece... 3 0
Cdc2-related kinase inhibitor N-[6-(3,5-dimethylphenyl)-1-meth... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 4 2
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 1
Urokinase plasminogen activator surface receptor ligand ethyl ... 1 0
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Ribosomal protein S6 kinase alpha-3 inhibitor (E)-3-[4-amino-7... 1 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
Adenosine receptor A1 ligand N-butyl-5-phenyl-3-[[2-(trifluoro... 7 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 2
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Tyrosine-protein kinase ABL1 and Abelson tyrosine-protein kina... 3 0
Translocator protein inhibitor CHEMBL2331870 family 2 0
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Cholinesterase inhibitor 4-[4,5-diphenyl-1-[7-(1,2,3,4-tetrahy... 2 1
Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-... 12 16
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 5
Melanin-concentrating hormone receptor 1 and Potassium voltage... 4 4
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... 2 0
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 1
Fatty acid-binding protein, adipocyte inhibitor AGN-PC-02W5KO ... 2 1
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 10 4
C-X-C chemokine receptor type 3 ligand AGN-PC-07CQOB family 17 10
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 16 7
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 3 0
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Disintegrin and metalloproteinase domain-containing protein 17... 4 0
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
C-X-C chemokine receptor type 3 ligand 1-[3-[[(1R,5S)-3-[[7-(t... 3 1
Melanin-concentrating hormone receptor 1 ligand (2S)-2-[[(3R,4... 2 0
Melanin-concentrating hormone receptor 1 and Mu-type opioid re... 2 0
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 7 2
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 10 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 22
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 11 5
Vascular endothelial growth factor receptor 2 and Vascular end... 1 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Corticotropin-releasing factor receptor 1 ligand SureCN7215846... 4 1
Substance-K receptor ligand SureCN9035669 family 10 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 2 0
Type-1 angiotensin II receptor ligand SureCN7390271 family 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand 1... 1 0
C-C chemokine receptor type 5 ligand 1-[4-(3-chlorophenyl)-4-[... 3 1
Gonadotropin-releasing hormone receptor ligand SureCN3275214 f... 5 0
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Type-1 angiotensin II receptor ligand AGN-PC-04X8EF family 1 1
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 0
Gonadotropin-releasing hormone receptor ligand 4-[[4-[2-(4-ter... 3 3
Gonadotropin-releasing hormone receptor and 5-hydroxytryptamin... 2 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
Nociceptin receptor and Mu-type opioid receptor ligand 2-(3-ch... 2 0
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Melanin-concentrating hormone receptor 1 ligand SureCN3832854 ... 3 2
Pteridine reductase, putative inhibitor 1-[(3,4-dichlorophenyl... 2 1
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 11 1
B1 bradykinin receptor ligand AGN-PC-077LWO family 2 0
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... 4 0
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
5-hydroxytryptamine receptor 2B ligand SureCN1299053 family 1 1
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Sonic hedgehog protein and Cytochrome P450 2C9 inhibitor AGN-P... 1 0
Neuropeptide Y receptor type 5 ligand AGN-PC-01NS1A family 7 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 9 0
Neuropeptide Y receptor type 5 ligand SureCN8149543 family 1 0
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(2-c... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 5
Tyrosine-protein kinase Lck and Tyrosine-protein kinase Lyn in... 1 0
P2Y purinoceptor 14 inhibitor AGN-PC-0A9S8H family 3 2
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 1 2
Mitogen-activated protein kinase kinase kinase 5 inhibitor 4-(... 2 0
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN8920007 f... 2 1
D(2) dopamine receptor and D(4) dopamine receptor ligand 3-[1-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00382830 CHEMBL1761111 Bioactive SureCN3335747
CFAMM00382829 CHEMBL1761114 Bioactive SureCN3338576
CFAMM00382828 CHEMBL1761098 Bioactive SureCN3334191
CFAMM00382831 CHEMBL1761106 Bioactive SureCN3335722

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27621 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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