CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7770
Family Name Fatty-acid amide hydrolase 1 inhibitor 3-[(3S)-1-[4-(5-chlorothiophen-2-yl)pyrimidin-2-yl]piperidin-3-yl]-1-ethylimidazo[4,5-b]pyridin-2-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00382915 Functional Category Bioactive
Superfamily Beta-lactamase and GABA theta subunit Binder Superfamily
Class Class 3430

Cousin Family NamesSeedsMembers
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 3 20
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Deoxycytidine kinase inhibitor AGN-PC-07Z9B3 family 2 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 6
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Corticotropin-releasing factor receptor 1 ligand 8-[butyl(ethy... 2 6
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0


External ID

Functional Category

Molecule Name

CFAMM00382915 CHEMBL1761301 Bioactive 3-[(3S)-1-[4-(5-chlorothiophen-2-yl)pyrimidin-2-yl]piperidin-3-yl]-1-ethylimidazo[4,5-b]pyridin-2-one
CFAMM00382913 CHEMBL1761302 Bioactive 3-[(3S)-1-[4-(5-chlorothiophen-2-yl)pyrimidin-2-yl]piperidin-3-yl]-1-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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