CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7783
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-PC-0A9SPY family
No. of Seeds 5 No. of Other Members 11
Family Centroid CFAMM00383017 Functional Category Bioactive
Superfamily Fibroblast growth factor receptor 1 and Insulin-like growth factor 1 receptor Ligand BMS-695735 Superfamily
Class Class 843

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 12 108
Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Family 8 56
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 19 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand N-(1h... 2 12
Cytochrome P450 3A4 Inhibitor 5-(2-phenethylpiperazin-1-yl)-1h... 12 35
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 33
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
cAMP-dependent protein kinase catalytic subunit PRKX and Ribos... 1 2
cAMP-dependent protein kinase catalytic subunit PRKX and Ribos... 1 1
Calcitonin gene-related peptide type 1 receptor ligand N-[2-(7... 5 3
C-C chemokine receptor type 3 ligand 1-(3-chloro-2H-indazol-5-... 1 1
Rho-associated protein kinase 2 inhibitor 1-(3-hydroxy-1-pheny... 3 3
Glucocorticoid receptor ligand 3,3,3-trifluoro-N-[(3S)-3-[1-(4... 10 4
Pol polyprotein inhibitor AC1LAMOI family 12 0
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand 1... 5 0
Cell division cycle 7-related protein kinase and Dual specific... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 1 0
P2X purinoceptor 7 inhibitor N-cyano-N'-(2-methylphenyl)-4-[2-... 2 1
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9057529 f... 2 0


External ID

Functional Category

Molecule Name

CFAMM00383017 CHEMBL1761864 Bioactive AGN-PC-0A9SPY
CFAMM00383020 CHEMBL1761863 Bioactive AGN-PC-0A9S3M
CFAMM00383028 CHEMBL355703 Bioactive benzimidazolone 16e
CFAMM00383019 CHEMBL1761860 Bioactive AGN-PC-0A9UNM

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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