CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM78
Family Name Corticotropin-releasing factor receptor 1 ligand N-(2-bromo-4-propan-2-ylphenyl)-N-ethyl-4-methyl-6-(2-phenylphenyl)pyrimidin-2-amine family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00306830 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 and Beta-lactamase Binder Superfamily
Class Class 3062

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
Metabotropic glutamate receptor 5 Ligand 2-(3-bromophenyl)-7-m... 3 1
Corticotropin-releasing factor receptor 1 ligand 4-N-(2-bromo-... 9 48
Adenosine kinase inhibitor abt-702 family 14 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-01ZUJC... 2 1
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 13 34
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 2
Dihydrofolate reductase inhibitor AC1LAKQL family 3 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00GBP0... 3 1
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 15 3
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 5 2
Corticotropin-releasing factor receptor 1 ligand SureCN8181501... 4 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 7
Corticotropin-releasing factor receptor 1 ligand AGN-PC-008HTV... 2 1
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0760... 4 0
Adenosine kinase inhibitor 5-(4-bromophenyl)-6-[2-[4-(dimethyl... 1 0
Adenosine kinase inhibitor AGN-PC-074DKZ family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00306831 CHEMBL266617 Bioactive AGN-PC-01ZUJF
CFAMM00306830 CHEMBL10189 Bioactive N-(2-bromo-4-propan-2-ylphenyl)-N-ethyl-4-methyl-6-(2-phenylphenyl)pyrimidin-2-amine
CFAMM00306829 CHEMBL10125 Bioactive SureCN8201414
CFAMM00306828 CHEMBL276184 Bioactive N-(2-bromo-4-propan-2-ylphenyl)-N-ethyl-4-methyl-6-naphthalen-1-ylpyrimidin-2-amine
CFAMM00306827 CHEMBL10175 Bioactive SureCN8210968

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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