CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM780
Family Name Substance-P receptor ligand (1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-7-pyridin-3-yl-2,3,8,8a-tetrahydro-1H-indolizin-5-one family
No. of Seeds 7 No. of Other Members 2
Family Centroid CFAMM00315801 Functional Category Bioactive
Superfamily Substance-P receptor Binder Superfamily 2
Class Class 3224

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxylamine Family 2 91
Cannabinoid receptor 1 Ligand Taranabant Family 20 30
G-protein coupled bile acid receptor 1 ligand 4-[[3,5-bis(trif... 1 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 7 1
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00315800 CHEMBL1090650 Bioactive (1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-7-(2-methylpyridin-4-yl)-2,3,8,8a-tetrahydro-1H-indolizin-5-one
CFAMM00315806 CHEMBL1090752 Bioactive (1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-7-pyridin-4-yl-2,3,8,8a-tetrahydro-1H-indolizin-5-one
CFAMM00315799 CHEMBL1090651 Bioactive (1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-7-(2-methoxypyridin-4-yl)-2,3,8,8a-tetrahydro-1H-indolizin-5-one
CFAMM00315805 CHEMBL1090649 Bioactive (1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-7-(2-fluoropyridin-4-yl)-2,3,8,8a-tetrahydro-1H-indolizin-5-one
CFAMM00315798 CHEMBL1090653 Bioactive (1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-7-(1-oxidopyridin-1-ium-3-yl)-2,3,8,8a-tetrahydro-1H-indolizin-5-one
CFAMM00315804 CHEMBL1090648 Bioactive (1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-7-(1-oxidopyridin-1-ium-4-yl)-2,3,8,8a-tetrahydro-1H-indolizin-5-one
CFAMM00315801 CHEMBL1089062 Bioactive (1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-7-pyridin-3-yl-2,3,8,8a-tetrahydro-1H-indolizin-5-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27527 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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