CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7808
Family Name Ephrin type-B receptor 4 and Vascular endothelial growth factor receptor 2 ligand AGN-PC-069IQX family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00167447 Functional Category Bioactive
Superfamily Dihydrofolate reductase and Dual specificity protein kinase TTK Binder Superfamily
Class Class 831

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
AP26113 family 16 90
JAK Inhibitor Momelotinib Family 33 83
RAC-gamma serine/threonine-protein kinase Inhibitor GSK690693 ... 16 27
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
Reverse transcriptase Inhibitor UK-129485 Family 23 221
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Dihydrofolate reductase inhibitor AC1L9XPA family 6 5
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Inositol monophosphatase 1 inhibitor CHEMBL1588383 family 1 6
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 6 12
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Ephrin type-B receptor 4 and Vascular endothelial growth facto... 1 4
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 11 2
Glucose-dependent insulinotropic receptor ligand propan-2-yl 4... 2 54
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 2
Toll-like receptor 7 ligand 4-amino-1-[[6-(2-pyrrolidin-1-ylet... 2 5
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 4 2
Cathepsin K and Cathepsin L1 inhibitor CHEBI:43424 family 2 0
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Epidermal growth factor receptor ligand N-[3-[3-methyl-7-[4-(4... 2 1
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-07... 1 0
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 7-cycl... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 18 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 4
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Epidermal growth factor receptor ligand N-[3-[2-(4-morpholin-4... 2 2
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
TGF-beta receptor type-1 ligand SureCN373216 family 3 14


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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