CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7809
Family Name Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform inhibitor AGN-PC-07ZI9L family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00383341 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 6 Binder Superfamily
Class Class 3139

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Tyrosine kinase Inhibitor PKI166 Family 17 198
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Oestrogen receptor and Estrogen receptor beta Ligand 4-(2-phen... 2 9
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
D(4) dopamine receptor Ligand A-425444 Family 2 10
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Proto-oncogene tyrosine-protein kinase Src and Cyclin-dependen... 2 1
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Neuropeptide Y receptor type 5 and Alpha-1A adrenergic recepto... 8 2
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 1 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 4 11
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Vascular endothelial growth factor receptor 2 and Vascular end... 4 2
Lysine--tRNA ligase inhibitor 4-[[[2-(2-piperazin-1-ylpyridin-... 2 1
Glutamate receptor ionotropic, NMDA 2B ligand 2-[[4-(4-chlorop... 4 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 11 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Tyrosine-protein kinase Lck inhibitor 3-[[2-(benzimidazol-1-yl... 2 0
5-hydroxytryptamine receptor 1A and Gonadotropin-releasing hor... 3 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-04UH85 family 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00383342 CHEMBL1762790 Bioactive AGN-PC-07ZVL7
CFAMM00383341 CHEMBL1762782 Bioactive AGN-PC-07ZI9L

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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