CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7815
Family Name Prothrombin inhibitor methyl 2-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2R)-2-(methylamino)-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]-1,3-benzothiazole-6-carboxylate family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00383390 Functional Category Bioactive
Superfamily Prothrombin and Beta-lactamase Binder Superfamily 7
Class Class 3901

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Prothrombin inhibitor (2S)-N-[(4-carbamimidoyl-1,3-thiazol-2-y... 3 2
Protease and Capsid scaffolding protein inhibitor AC1LAC7K family 2 5
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 3 3
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
Prolyl endopeptidase inhibitor 1,3-benzothiazol-2-yl-[(2S)-1-[... 2 1
Prothrombin inhibitor N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(... 10 15
Prothrombin inhibitor 6-[3-(4-acetylpiperazin-1-yl)-3-oxopropy... 4 1
Prothrombin inhibitor N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00383388 CHEMBL176491 Bioactive 2-[5-(diaminomethylideneamino)-2-[[(2S)-1-[(2R)-2-(methylamino)-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]-1,3-benzothiazole-6-carboxylic acid
CFAMM00383390 CHEMBL272334 Bioactive methyl 2-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2R)-2-(methylamino)-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]-1,3-benzothiazole-6-carboxylate
CFAMM00383389 CHEMBL403929 Bioactive RWJ-51438

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44688 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543