CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7817
Family Name Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3A4 inhibitor SureCN5688348 family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00213608 Functional Category Bioactive
Superfamily Alpha-2A adrenergic receptor and Cytochrome P450 3A4 Binder Superfamily
Class Class 975

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Histamine H3 receptor Ligand Proxyfan Family 12 32
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 16
Adenosine receptor A1 and Adenosine receptor A2b ligand 2-amin... 4 0
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 5 14
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Histamine H3 receptor ligand AGN-PC-075YUJ family 2 0
Histamine H3 receptor ligand AGN-PC-075YXY family 1 4
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 5
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
Glucocorticoid receptor ligand SureCN12238714 family 16 4
Serine/threonine-protein kinase mTOR inhibitor 3-(cyclohexylme... 2 1
Alpha-2A adrenergic receptor and Alpha-1A adrenergic receptor ... 1 3
Putative NP ZINC32497112 Family 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27751 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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