CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7826
Family Name Corticotropin-releasing factor receptor 1 ligand 7-[bis(2-methoxyethyl)amino]-5-methyl-3-(2,4,6-trimethylphenyl)-[1,3]thiazolo[4,5-d]pyrimidine-2-thione family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00383458 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Binder Superfamily 8
Class Class 1246

Cousin Family NamesSeedsMembers
GDC-0349 family 44 77
Toll-like receptor 7 Ligand GS-9620 Family 2 4
Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
Corticotropin-releasing factor receptor 1 ligand 4-N-(2-bromo-... 9 48
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 15 3
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 5 2
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Corticotropin-releasing factor receptor 1 ligand SureCN8181501... 4 2


External ID

Functional Category

Molecule Name

CFAMM00383460 CHEMBL17656 Bioactive 7-[bis(2-methoxyethyl)amino]-5-methyl-3-(2,4,6-trimethylphenyl)-[1,3]thiazolo[4,5-d]pyrimidin-2-one
CFAMM00383459 CHEMBL413968 Bioactive 7-(diethylamino)-5-methyl-3-(2,4,6-trimethylphenyl)-[1,3]thiazolo[4,5-d]pyrimidine-2-thione
CFAMM00383458 CHEMBL417091 Bioactive 7-[bis(2-methoxyethyl)amino]-5-methyl-3-(2,4,6-trimethylphenyl)-[1,3]thiazolo[4,5-d]pyrimidine-2-thione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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