CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7839
Family Name Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor AGN-PC-0A9QR8 family
No. of Seeds 5 No. of Other Members 17
Family Centroid CFAMM00383533 Functional Category Bioactive
Superfamily Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor TAK-700 Superfamily
Class Class 307

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Prothrombin Inhibitor Dabigatran Family 7 182
Thromboxane-A synthase Inhibitor CGS-13080 Family 3 19
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor CI-9... 3 13
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 3-(6-amin... 5 10
Cytochrome P450 26A1 inhibitor AGN-PC-09MAZ1 family 2 1
Cytochrome P450 26A1 inhibitor SureCN4280032 family 1 1
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor methyl ... 1 2
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Cytochrome P450 26A1 inhibitor methyl 3-[4-[(6-bromopyridin-3-... 1 1
Cytochrome P450 11B1, mitochondrial and Cytochrome P450 11B2, ... 3 4
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
Cytochrome P450 26A1 inhibitor 4-[4-[2-carboxy-2-methyl-1-(1,2... 1 0


External ID

Functional Category

Molecule Name

CFAMM00383537 CHEMBL1831083 Bioactive ethyl 3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propanoate
CFAMM00383533 CHEMBL1766005 Bioactive AGN-PC-0A9QR8
CFAMM00383536 CHEMBL1766000 Bioactive AGN-PC-09MAW3
CFAMM00383535 CHEMBL1766003 Bioactive SureCN4283372
CFAMM00383529 CHEMBL2146981 Bioactive methyl 3-imidazol-1-yl-2,2-dimethyl-3-[4-[4-(trifluoromethyl)anilino]phenyl]propanoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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