CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM784
Family Name Melanocortin receptor 4 and Potassium voltage-gated channel subfamily H member 2 ligand [(3R,4S)-4-(2,4-difluorophenyl)-1-pyridin-3-ylpyrrolidin-3-yl]-[(3S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl]methanone family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00315828 Functional Category Bioactive
Superfamily Melanocortin receptor 4 and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 3224

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
PF-4136309 family 16 27
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 5 69
Potassium voltage-gated channel subfamily H member 2 and Melan... 2 8
C-C chemokine receptor type 5 ligand AC1LA25C family 3 6
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 1
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 2 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
Renin and Potassium voltage-gated channel subfamily H member 2... 13 11
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Platelet-activating factor receptor ligand SureCN9852997 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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