CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7851
Family Name Bifunctional epoxide hydrolase 2 and Prostaglandin G/H synthase 2 inhibitor AGN-PC-09MB3B family
No. of Seeds 7 No. of Other Members 20
Family Centroid CFAMM00383679 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 Inhibitor Celecoxib Superfamily
Class Class 428

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Celecoxib Family 3 97
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
Bifunctional epoxide hydrolase 2 and Prostaglandin G/H synthas... 2 0
Proto-oncogene tyrosine-protein kinase Src inhibitor AGN-PC-00... 3 20
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(1-methy... 1 4
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
Neuropeptide Y receptor type 5 ligand AGN-PC-074HS9 family 2 5
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 3 8
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C9 l... 2 5
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 3


External ID

Functional Category

Molecule Name

CFAMM00383669 CHEMBL1766286 Bioactive AGN-PC-09MB6O
CFAMM00383693 CHEMBL1766301 Bioactive AGN-PC-09MB3C
CFAMM00383668 CHEMBL1766284 Bioactive AGN-PC-09MB6M
CFAMM00383671 CHEMBL1766283 Bioactive AGN-PC-09MB6L
CFAMM00383679 CHEMBL1766299 Bioactive AGN-PC-09MB3B
CFAMM00383670 CHEMBL1766287 Bioactive AGN-PC-09MB9O
CFAMM00383694 CHEMBL1766300 Bioactive AGN-PC-09MB3A

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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