CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7857
Family Name Hepatocyte growth factor receptor ligand AGN-PC-08XYH0 family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00383718 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor Binder Superfamily
Class Class 1022

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Ximelegatran Family 8 157
Glucagon receptor Ligand Dwlip-gcgrrx Family 5 26
Amg 423 family 7 47
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Hepatocyte growth factor receptor Ligand 1-benzyl-1h-pyrrolo[3... 2 16
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Protein kinase C theta type and Protein kinase C delta type in... 16 8
Serine/threonine-protein kinase mTOR and DNA-dependent protein... 6 7
Glutamate receptor 1 and Glutamate receptor 2 ligand 2-[2,3-di... 3 23
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 2
Hepatocyte growth factor receptor ligand AGN-PC-08XYH3 family 1 0
Hepatocyte growth factor receptor ligand AGN-PC-09M1N4 family 2 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 3 1
CGMP-dependent protein kinase inhibitor 1-[4-acetyl-3-[[4-[5-(... 2 0
CGMP-dependent protein kinase inhibitor AGN-PC-078XQ0 family 1 1
Dihydrofolate reductase type 1 and Dihydrofolate reductase inh... 1 0
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 8
Transient receptor potential cation channel subfamily V member... 1 0
Hepatocyte growth factor receptor ligand AGN-PC-050CDR family 1 0


External ID

Functional Category

Molecule Name

CFAMM00383713 CHEMBL1766546 Bioactive AGN-PC-09M1PN
CFAMM00383725 CHEMBL1766539 Bioactive AGN-PC-09M1KD
CFAMM00383718 CHEMBL1766528 Bioactive AGN-PC-08XYH0
CFAMM00383724 CHEMBL1766538 Bioactive AGN-PC-09M1KC
CFAMM00383717 CHEMBL1766529 Bioactive AGN-PC-08XYH1
CFAMM00383715 CHEMBL1766544 Bioactive AGN-PC-09M1N6
CFAMM00383722 CHEMBL1766530 Bioactive AGN-PC-08XYH2
CFAMM00383721 CHEMBL1766532 Bioactive AGN-PC-09M1HL

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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