CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7863
Family Name Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-N,N-dimethyl-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide family
No. of Seeds 15 No. of Other Members 2
Family Centroid CFAMM00383748 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Binder Superfamily 10
Class Class 3226

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor Apixaban Family 34 52
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Coagulation factor X and Prothrombin Inhibitor BMS-740808 Family 64 8
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Coagulation factor X inhibitor AGN-PC-00FGDC family 11 5
Translocator protein inhibitor N-(4-methoxyphenyl)-N,3-dimethy... 2 2
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 17 4
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Coagulation factor X inhibitor 1-(4-methoxyphenyl)-7-oxo-6-[4-... 5 0
Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphe... 8 0
Coagulation factor X inhibitor AGN-PC-03K47Q family 3 0
Coagulation factor X inhibitor AGN-PC-046QD2 family 6 0
Coagulation factor X inhibitor SureCN6785555 family 7 0
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 1 0
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 7 0
Coagulation factor X inhibitor AGN-PC-046RMQ family 1 0
Vascular endothelial growth factor receptor 2 and Vascular end... 2 3
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
Coagulation factor X inhibitor SureCN5641901 family 5 0
Coagulation factor X inhibitor AGN-PC-077MYE family 16 0
Coagulation factor X inhibitor SureCN5644036 family 30 0
Coagulation factor X inhibitor AGN-PC-077MVW family 5 0
Coagulation factor X inhibitor SureCN5644554 family 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00383750 CHEMBL237419 Bioactive AGN-PC-00KCL4
CFAMM00383743 CHEMBL236752 Bioactive 3-amino-6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one
CFAMM00383749 CHEMBL238301 Bioactive tert-butyl N-[6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridin-3-yl]carbamate
CFAMM00383748 CHEMBL235492 Bioactive 6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-N,N-dimethyl-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide
CFAMM00383747 CHEMBL1766823 Bioactive AGN-PC-046QCZ
CFAMM00383746 CHEMBL237420 Bioactive AGN-PC-031BDR
CFAMM00383752 CHEMBL235064 Bioactive 3-(dimethylamino)-6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one
CFAMM00383745 CHEMBL237441 Bioactive 6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylic acid
CFAMM00383751 CHEMBL399822 Bioactive 6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-3-(methylamino)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one
CFAMM00383744 CHEMBL235268 Bioactive 6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-1-(4-methoxyphenyl)-N-methyl-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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