CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7865
Family Name Matrix metalloproteinase-14 and A disintegrin and metalloproteinase with thrombospondin motifs 5 inhibitor (1S,2R,3R)-1-[(6-fluoro-4H-thieno[3,2-b]indol-2-yl)sulfonylamino]-2-methyl-3-phenylcyclopropane-1-carboxylic acid family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00383766 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 6
Class Class 2185

Cousin Family NamesSeedsMembers
Endothelin B receptor Ligand IRL-2500 Family 34 87
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 5 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 2


External ID

Functional Category

Molecule Name

CFAMM00383766 CHEMBL1766904 Bioactive (1S,2R,3R)-1-[(6-fluoro-4H-thieno[3,2-b]indol-2-yl)sulfonylamino]-2-methyl-3-phenylcyclopropane-1-carboxylic acid
CFAMM00383765 CHEMBL1766905 Bioactive (1S,2R,3R)-1-[(7-fluoro-4H-thieno[3,2-b]indol-2-yl)sulfonylamino]-2-methyl-3-phenylcyclopropane-1-carboxylic acid
CFAMM00383767 CHEMBL1766903 Bioactive (1S,2R,3R)-1-[(6-chloro-4H-thieno[3,2-b]indol-2-yl)sulfonylamino]-2-methyl-3-phenylcyclopropane-1-carboxylic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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