CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7869
Family Name Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-methoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00146618 Functional Category Bioactive with Natural Product
Superfamily Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004723 Superfamily
Class Class 989

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 13 18
Irdabisant family 49 53
Elagolix family 43 98
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 7 9
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 2 0
Survival motor neuron protein inhibitor CHEMBL1303282 family 1 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 4
Histamine H3 receptor ligand SureCN1373218 family 2 2
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand 3-methyl-1-[4-(3-piperidin-1-ylpr... 6 1
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 7 13
Histamine H3 receptor ligand 4-[[2-[2-[(2R)-2-methylpyrrolidin... 1 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor (4aS... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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