CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7870
Family Name Coagulation factor X inhibitor AGN-PC-078Y3A family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00383786 Functional Category Bioactive
Superfamily Coagulation factor X and cAMP-specific 3',5'-cyclic phosphodiesterase 4A Binder Superfamily
Class Class 1209

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Transient receptor potential cation channel subfamily V member... 16 295
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
XL-888 family 16 85
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Tubulin beta chain Inhibitor 2-(3-chloro-phenyl)-1h-[1,8]napht... 3 13
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... 3 5
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
Nicotinamide phosphoribosyltransferase inhibitor 4-[(7-chloro-... 6 4
Coagulation factor X inhibitor AGN-PC-075AY8 family 28 21
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Coagulation factor X inhibitor AGN-PC-078Y4E family 4 6
Hepatocyte growth factor receptor and Insulin receptor ligand ... 4 15
C-X-C chemokine receptor type 3 ligand SureCN13205646 family 4 0
Coagulation factor X and Kallikrein-1 inhibitor SureCN890858 f... 5 6
Nicotinamide phosphoribosyltransferase inhibitor 4-[[(7-chloro... 1 1
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
C-X-C chemokine receptor type 3 ligand 5-[(3S)-4-[1-(4-chlorob... 6 0
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[3-(4-chlorop... 4 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X3N ... 1 7
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 2 1
Protein kinase C theta type inhibitor (2-aminopyridin-3-yl)-[6... 4 1
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
Coagulation factor X inhibitor 5-chloro-N-(5-chloropyridin-2-y... 6 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (4-am... 2 1
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Coagulation factor X inhibitor 5-bromo-N-(5-chloropyridin-2-yl... 1 1
Coagulation factor X inhibitor AGN-PC-078Y0S family 7 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 0
Thromboxane-A synthase inhibitor 6-chloro-3-(4-imidazol-1-ylbu... 12 21
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Cannabinoid receptor 2 ligand N-isoquinolin-1-yl-4-methyl-3-pi... 1 0
Macrophage colony-stimulating factor 1 receptor ligand N-[3-[(... 5 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Potassium ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00383787 CHEMBL472599 Bioactive AGN-PC-078Y3B
CFAMM00383786 CHEMBL472598 Bioactive AGN-PC-078Y3A
CFAMM00383785 CHEMBL471921 Bioactive AGN-PC-078Y3G
CFAMM00383781 CHEMBL176757 Bioactive 5-chloro-N-(5-chloropyridin-2-yl)-2-[[4-[[4,5-dihydro-1,3-thiazol-2-yl(methyl)amino]methyl]benzoyl]amino]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27513 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543