CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7884
Family Name Calcitonin gene-related peptide type 1 receptor ligand SureCN12219678 family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00383876 Functional Category Bioactive
Superfamily Calcitonin gene-related peptide type 1 receptor and Integrin beta-3 Binder Superfamily
Class Class 3274

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Prothrombin Inhibitor Dabigatran Family 7 182
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Translocator protein Inhibitor Emapunil Family 7 89
Adenosine receptor A1 Ligand SLV320 Family 6 79
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
GDC-0349 family 44 77
JAK Inhibitor Momelotinib Family 33 83
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 7 72
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 2 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 7 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 7 6
S-methyl-5'-thioadenosine phosphorylase inhibitor SureCN997478... 8 0
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Prelamin-A/C and Lethal(3)malignant brain tumor-like protein 1... 1 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
C-C chemokine receptor type 5 ligand [4-[2-[3-(2-ethylbenzimid... 5 12
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Toll-like receptor 7 ligand 4-amino-1-[[6-[(2S)-2-(pyrrolidin-... 4 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
3-phosphoinositide-dependent protein kinase 1 and RAC-alpha se... 10 4
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family 7 29
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 1 0
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 3 4
Transient receptor potential cation channel subfamily V member... 4 0
Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... 2 2
Renin inhibitor AGN-PC-073MLF family 7 6
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 7-cycl... 1 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152412 family 8 0
Succinate receptor 1 ligand N-[[4-(3-methylphenyl)phenyl]methy... 2 14
Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... 7 0
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 11 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 0
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-[2-(trif... 1 0
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
Serine/threonine-protein kinase mTOR inhibitor 2-[4-[4-[(3S)-3... 3 0
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0
Serine/threonine-protein kinase PLK2 and Serine/threonine-prot... 1 2
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 0
Gonadotropin-releasing hormone receptor ligand 1-[2-(3,5-dimet... 3 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 3 0
Aurora kinase B and Aurora kinase A inhibitor 1-cyclohexyl-3-[... 4 0
Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family 2 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00383875 CHEMBL1770715 Bioactive SureCN12219687
CFAMM00383874 CHEMBL1770560 Bioactive SureCN12219667
CFAMM00383873 CHEMBL1770563 Bioactive SureCN12219676
CFAMM00383878 CHEMBL1770718 Bioactive SureCN12219715
CFAMM00383877 CHEMBL1770719 Bioactive SureCN12219714
CFAMM00383876 CHEMBL1770714 Bioactive SureCN12219678

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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