CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7918
Family Name Muscarinic acetylcholine receptor M3 and Beta-2 adrenergic receptor ligand N-[3-[3-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxyphenyl]propyl]-2-[3-[2-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]-2-methylpropyl]phenyl]acetamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00007520 Functional Category Bioactive
Superfamily Beta-2 adrenergic receptor and Muscarinic acetylcholine receptor M3 Binder Superfamily
Class Class 4595

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Thymopentin family 20 133
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 20 35
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Estradiol 17-beta-dehydrogenase 1 Inhibitor N-isopropyl Estrad... 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pr... 8 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 20 7
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 3 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 3 0
Phenylalanine--tRNA ligase alpha subunit inhibitor TCMDC-14030... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00384059 CHEMBL402501 Bioactive SureCN523340
CFAMM00384058 CHEMBL230486 Bioactive SureCN4384659
CFAMM00384057 CHEMBL230203 Bioactive SureCN4386813

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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