CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7924
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Serine/threonine-protein kinase mTOR inhibitor AGN-PC-093O35 family
No. of Seeds 5 No. of Other Members 7
Family Centroid CFAMM00384142 Functional Category Bioactive
Superfamily Glucokinase and cAMP Binder Superfamily
Class Class 834

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 42 32
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Survival motor neuron protein and Microtubule-associated prote... 1 20
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Sodium channel protein type 9 subunit alpha ligand 4-[2-(6-ami... 1 8
Sodium channel protein type 9 subunit alpha ligand 4-[2-(2-ami... 3 3
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 6
Prelamin-A/C and Ferritin light chain inhibitor F2515-0224 family 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 3
A disintegrin and metalloproteinase with thrombospondin motifs... 2 4


External ID

Functional Category

Molecule Name

CFAMM00384137 CHEMBL1773604 Bioactive AGN-PC-093OAD
CFAMM00384140 CHEMBL1773600 Bioactive AGN-PC-093O37
CFAMM00384142 CHEMBL1773599 Bioactive AGN-PC-093O35
CFAMM00384139 CHEMBL1773603 Bioactive AGN-PC-093OAC
CFAMM00384138 CHEMBL1773602 Bioactive AGN-PC-093OAA

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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