CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7942
Family Name Sigma non-opioid intracellular receptor 1 ligand BAS 04057753 family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00384251 Functional Category Bioactive with Natural Product
Superfamily Survival motor neuron protein and Retinal dehydrogenase 1 Binder Superfamily
Class Class 3647

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Endothelin-1 receptor Ligand Atrasentan Family 127 336
D(3) dopamine receptor Ligand U-99194A Family 7 33
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 24
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Intercellular adhesion molecule 1 Inhibitor Dehydropipernonali... 5 36
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
5-hydroxytryptamine receptor 1A ligand SureCN7035190 family 10 17
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
Regulator of G-protein signaling 12 and Beta-lactamase inhibit... 1 7
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Carbonic anhydrase 14 and Carbonic anhydrase 9 inhibitor 1-(4-... 2 3
Melanin-concentrating hormone receptor 1 ligand 6-methoxy-4-[[... 2 15
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Dipeptidyl peptidase 4 inhibitor SureCN8267584 family 1 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Putative Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methy... 2 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Chymase inhibitor 1,3-bis[(3-methoxyphenyl)methyl]-1,3-diazeti... 3 1
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5
Mu-type opioid receptor ligand N-[2-[(2-amino-2-oxoethyl)-[2-(... 1 0
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 10
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (E)-... 1 0
D(2) dopamine receptor ligand AGN-PC-00PT7Q family 2 1
Benzazepines Metabolite N-Methylporphyroxine Family 1 2
NP N-(3,4-dimethoxyphenethyl)-2-(2-(hydroxymethyl)-5-methoxy-4... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00384249 CHEMBL1774732 Bioactive AC1LGD4Q
CFAMM00384258 CHEMBL2314424 Bioactive 1-(1,3-benzodioxol-5-ylmethyl)-4-[[4-(2-fluoroethoxy)phenyl]methyl]piperazine
CFAMM00384252 CHEMBL1774729 Bioactive BAS 01840661
CFAMM00384251 CHEMBL1774728 Bioactive BAS 04057753
CFAMM00384250 CHEMBL1774730 Bioactive AGN-PC-09MBXE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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