CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7953
Family Name Aurora kinase A inhibitor AGN-PC-0A9UUA family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00384330 Functional Category Bioactive
Superfamily Aurora kinase A and Tyrosine-protein kinase Yes Binder Superfamily
Class Class 4596

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(4-a... 8 11
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 4
Aurora kinase A and Tyrosine-protein kinase Yes inhibitor AGN-... 4 0
Aurora kinase B and Aurora kinase A inhibitor 2-[(3S,4S)-3-hyd... 22 5
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-09QXA7 fa... 16 0
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 7 0
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 2 0
Aurora kinase A inhibitor SureCN2205392 family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00384332 CHEMBL1780258 Bioactive AGN-PC-0A9SB6
CFAMM00384330 CHEMBL1777841 Bioactive AGN-PC-0A9UUA
CFAMM00384329 CHEMBL1778660 Bioactive AGN-PC-0A9QD3
CFAMM00384333 CHEMBL1780257 Bioactive AGN-PC-0A9TKC

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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