CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7955
Family Name B1 bradykinin receptor ligand SureCN13936521 family
No. of Seeds 19 No. of Other Members 4
Family Centroid CFAMM00384354 Functional Category Bioactive
Superfamily B1 bradykinin receptor and B2 bradykinin receptor Binder Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
B1 bradykinin receptor ligand SureCN4136698 family 6 33
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 6 7
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
B1 bradykinin receptor ligand 2-[1-(4-chlorophenyl)sulfonyl-3-... 5 9
Bifunctional epoxide hydrolase 2 inhibitor N-cycloheptyl-1-(2,... 7 8
B1 bradykinin receptor ligand N-[(1R)-6-[(dimethylamino)methyl... 7 6
B1 bradykinin receptor ligand N-[(4R)-1,1-dioxo-3,4-dihydro-2H... 1 0
B1 bradykinin receptor ligand N-[(4S)-1-ethyl-3,3-dimethylpipe... 10 4
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 1 0
B1 bradykinin receptor ligand SureCN5950627 family 2 11
Motilin receptor ligand N-[[2-[4-[[(3S,5R)-3,5-dimethylpiperaz... 2 0
B1 bradykinin receptor ligand SureCN5405184 family 1 0
B1 bradykinin receptor ligand SureCN5392679 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00384361 CHEMBL1777974 Bioactive SureCN4957940
CFAMM00384348 CHEMBL1777966 Bioactive SureCN4957968
CFAMM00384355 CHEMBL1777887 Bioactive SureCN4515578
CFAMM00384367 CHEMBL1777954 Bioactive 2-[3-oxo-1-[3-(trifluoromethyl)phenyl]sulfonylpiperazin-2-yl]-N-[(1R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide
CFAMM00384360 CHEMBL1777972 Bioactive SureCN4530961
CFAMM00384366 CHEMBL1777979 Bioactive SureCN4958257
CFAMM00384354 CHEMBL1777885 Bioactive SureCN13936521
CFAMM00384359 CHEMBL1777971 Bioactive SureCN4957986
CFAMM00384365 CHEMBL1777978 Bioactive SureCN4959686
CFAMM00384352 CHEMBL1777969 Bioactive 2-[(2R)-1-(4-methylphenyl)sulfonyl-3-oxopiperazin-2-yl]-N-[(1R)-6-[(4-methylpiperidin-1-yl)methyl]-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide
CFAMM00384358 CHEMBL1777970 Bioactive N-[(1R)-6-[(3,3-dimethylpiperidin-1-yl)methyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-[(2R)-1-(4-methylphenyl)sulfonyl-3-oxopiperazin-2-yl]acetamide
CFAMM00384364 CHEMBL1777977 Bioactive SureCN4957055
CFAMM00384370 CHEMBL1777958 Bioactive SureCN4957132
CFAMM00384363 CHEMBL1777976 Bioactive SureCN4522240
CFAMM00384350 CHEMBL1777960 Bioactive SureCN13936516
CFAMM00384362 CHEMBL1777975 Bioactive SureCN4958177
CFAMM00384349 CHEMBL1777965 Bioactive SureCN4523877
CFAMM00384356 CHEMBL1777881 Bioactive 2-[1-(benzenesulfonyl)-3-oxopiperazin-2-yl]-N-[(1R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide
CFAMM00384368 CHEMBL1777955 Bioactive 2-[1-[4-methyl-3-(trifluoromethyl)phenyl]sulfonyl-3-oxopiperazin-2-yl]-N-[(1R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Professor in Department of Pharmacy
National University of Singapore, Singapore

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