CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7962
Family Name Prostaglandin D2 receptor 2 ligand SureCN2189431 family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00384407 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor Binder Superfamily
Class Class 1029

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
Substance-P receptor Ligand GSK424887 Family 8 184
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Growth hormone receptor Ligand EP-51216 Family 34 390
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Setipiprant family 5 118
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
Lethal factor Inhibitor GM6001 Family 50 435
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Endothelin B receptor Ligand IRL-2500 Family 34 87
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 4 19
NS5B protein inhibitor AC1NQMYG family 6 12
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4R,... 3 7
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 6
Histamine H3 receptor ligand AGN-PC-04YWRD family 5 13
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... 3 2
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 5 8
Somatostatin receptor type 4 ligand methyl 5-(diaminomethylide... 2 34
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 5 1
Prostaglandin D2 receptor 2 ligand 2-[(8R)-8-[(4-fluorophenyl)... 3 15
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 20 37
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 5 2
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
Prothrombin and Trypsin-1 inhibitor 1-[2-(4-benzylpiperidin-1-... 2 2
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
NS5B protein inhibitor AC1O5AET family 3 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
NS5B protein inhibitor AC1NQMYP family 5 0
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Translocator protein inhibitor N,N-diethyl-11-(2-fluoroethyl)-... 14 9
Cannabinoid receptor 1 ligand (2-cyclopentyl-5-prop-2-enyl-3,4... 3 8
Prostaglandin D2 receptor 2 ligand 2-[1-(4-benzamidobenzoyl)is... 4 9
Egl nine homolog 1 inhibitor 1'-[(3-methylpyridin-2-yl)methyl]... 6 4
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Substance-P receptor ligand SureCN7796965 family 9 1
Substance-P receptor ligand SureCN7790374 family 6 0
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(1-cyanocyclop... 10 7
C-C chemokine receptor type 2 ligand 2-[4-(5-amino-1H-indol-3-... 3 2
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Substance-P receptor ligand AGN-PC-004REJ family 3 0
Mu-type opioid receptor ligand MITRAGYNINE family 2 8
Phospholipase A2, membrane associated inhibitor AGN-PC-075RBK ... 1 2
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
Phospholipase A2, membrane associated inhibitor 4-[3-(2-amino-... 2 0
A disintegrin and metalloproteinase with thrombospondin motifs... 2 12
D(2) dopamine receptor and D(3) dopamine receptor ligand methy... 2 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 48


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00384408 CHEMBL1778523 Bioactive SureCN2187260
CFAMM00384407 CHEMBL1778522 Bioactive SureCN2189431
CFAMM00384406 CHEMBL1778525 Bioactive SureCN2188220
CFAMM00384412 CHEMBL1778506 Bioactive SureCN2188674
CFAMM00384405 CHEMBL1778524 Bioactive SureCN2188929
CFAMM00384411 CHEMBL1778388 Bioactive SureCN2189353
CFAMM00384410 CHEMBL1778387 Bioactive 2-[(7R)-7-[[(2R)-2-(4-fluorophenyl)propanoyl]-methylamino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27513 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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