CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7967
Family Name Neprilysin and Natriuretic peptides A inhibitor (2S)-2-[[1-[[(1S)-1-carboxy-2-(5-phenyl-1,3-oxazol-2-yl)ethyl]carbamoyl]cyclopentyl]amino]-4-methoxybutanoic acid family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00330183 Functional Category Bioactive
Superfamily Neprilysin and Neutrophil elastase Binder Superfamily
Class Class 369

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(5-phenyloxa... 3 3
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(furan-2-yl)oxazol... 2 1
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Fatty-acid amide hydrolase 1 inhibitor SureCN1471727 family 2 19
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Caspase-3 and Caspase-1 inhibitor (3S)-3-[2-[3-[(4-methyl-1,2,... 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Collagenase 3 inhibitor AGN-PC-03HW1J family 4 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 3


External ID

Functional Category

Molecule Name

CFAMM00384447 CHEMBL1778534 Bioactive (2S)-2-[[1-[[(1S)-1-carboxy-2-[5-(4-chlorophenyl)-1,3-oxazol-2-yl]ethyl]carbamoyl]cyclopentyl]amino]-4-methoxybutanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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