CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM7975
Family Name Ghrelin/growth hormone secretagogue receptor ligand AGN-PC-00AL2E family
No. of Seeds 7 No. of Other Members 27
Family Centroid CFAMM00384546 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 35
Class Class 882

Cousin Family NamesSeedsMembers
Kinesin-like protein KIF11 Inhibitor Ispinesib Family 4 37
Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-ph... 3 137
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Histone deacetylase 6 and Histone deacetylase 8 inhibitor (E)-... 2 8
Poly [ADP-ribose] polymerase 1 inhibitor 8-chloro-2-[(3S)-3-(4... 2 8
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
Inositol monophosphatase 1 and Retinal dehydrogenase 1 inhibit... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
Acetylcholinesterase and Cholinesterase inhibitor N-[4-[(E)-(6... 1 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 4-oxo... 3 1
C-X-C chemokine receptor type 3 ligand N-[2-(dimethylamino)eth... 3 4
Delta-type opioid receptor ligand SureCN7549631 family 6 3
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN621... 1 3


External ID

Functional Category

Molecule Name

CFAMM00384546 CHEMBL243697 Bioactive AGN-PC-00AL2E
CFAMM00384568 CHEMBL243888 Bioactive AGN-PC-046ICI
CFAMM00384544 CHEMBL1778953 Bioactive AGN-PC-0A9QEO
CFAMM00384552 CHEMBL243700 Bioactive AGN-PC-046ICH
CFAMM00384561 CHEMBL243000 Bioactive AGN-PC-046ICG
CFAMM00384570 CHEMBL243886 Bioactive AGN-PC-046I5I

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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