CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Mitogen-activated protein kinase 14 inhibitor AGN-PC-07C64P family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00315975 Functional Category Bioactive
Superfamily B1 bradykinin receptor and Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 1152

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 5 Ligand N-(1,3-diphenyl-1h-py... 6 37
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZYJE fa... 15 5
Mitogen-activated protein kinase 14 inhibitor SureCN3632376 fa... 10 5
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Glucocorticoid receptor ligand N-ethyl-2-fluoro-N-[3,3,3-trifl... 16 7
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 5 10
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 6 0
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Glucocorticoid receptor ligand 5-amino-N-[(2R)-2-[[(2,6-dichlo... 6 5


External ID

Functional Category

Molecule Name

CFAMM00315974 CHEMBL562527 Bioactive AGN-PC-07C46W
CFAMM00315980 CHEMBL558448 Bioactive SureCN3973843
CFAMM00315985 CHEMBL1091928 Bioactive SureCN3632963
CFAMM00315979 CHEMBL564054 Bioactive SureCN3978687
CFAMM00315984 CHEMBL560390 Bioactive AGN-PC-07C4OP
CFAMM00315976 CHEMBL1089456 Bioactive SureCN3636158
CFAMM00315975 CHEMBL550519 Bioactive AGN-PC-07C64P
CFAMM00315981 CHEMBL561932 Bioactive AGN-PC-076VCE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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