CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor 1A ligand SureCN7035190 family
No. of Seeds 10 No. of Other Members 17
Family Centroid CFAMM00305862 Functional Category Bioactive with Natural Product
Superfamily Monoglyceride lipase and Fatty-acid amide hydrolase 1 Binder Superfamily
Class Class 719

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
Sigma non-opioid intracellular receptor 1 ligand BAS 04057753 ... 5 8
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Putative Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methy... 2 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26
Benzazepines Metabolite N-Methylporphyroxine Family 1 2


External ID

Functional Category

Molecule Name

CFAMM00305866 CHEMBL95995 Bioactive SureCN9035720
CFAMM00305855 CHEMBL98412 Bioactive SureCN9035890
CFAMM00305865 CHEMBL319368 Bioactive SureCN9036819
CFAMM00305880 CHEMBL319175 Bioactive AGN-PC-074RMC
CFAMM00305863 CHEMBL317769 Bioactive AGN-PC-074RM7
CFAMM00305872 CHEMBL319132 Bioactive AGN-PC-074RMH
CFAMM00305879 CHEMBL98984 Bioactive AGN-PC-074RM6
CFAMM00305871 CHEMBL99401 Bioactive AGN-PC-074RM8
CFAMM00305852 CHEMBL100086 Bioactive SureCN9035305
CFAMM00305862 CHEMBL318411 Bioactive SureCN7035190

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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