CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8013
Family Name Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00CFYH family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00384778 Functional Category Bioactive
Superfamily Cytochrome P450 2C9 and Muscleblind-like protein 1 Binder Superfamily
Class Class 1991

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
DNA Binder Elliptinium Acetate Family 11 116
Citric Acid family 2 58
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Oestrogen receptor and Estrogen receptor beta Ligand ZK-119010... 2 16
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Oestrogen receptor and Estrogen receptor beta Ligand Estrogen ... 7 2
Acetylcholinesterase and Cholinesterase Inhibitor 6-hydroxy-1,... 4 2
Cytochrome P450 11B1, mitochondrial Inhibitor 5-(6-methoxynaph... 7 4
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3,3'-pyrazine-2,5-... 2 14
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Glucocorticoid receptor Ligand 1-(3-chloro-4-fluorophenyl)-2,2... 1 13
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 9 22
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 5
Glucocorticoid receptor ligand [(4aR,5S)-1-(4-fluorophenyl)-4a... 7 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 10
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 33 5
Serine/threonine-protein kinase Chk1 inhibitor SureCN6786541 f... 3 6
Serine/threonine-protein kinase B-raf and Mitogen-activated pr... 16 5
Serine/threonine-protein kinase B-raf and RAF proto-oncogene s... 10 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 7 1
Androgen receptor ligand SureCN1990713 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00384778 CHEMBL1780161 Bioactive AGN-PC-00CFYH

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26393 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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