CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8020
Family Name Coagulation factor VII and Trypsin-1 inhibitor (2S)-2-[[(2R)-2-[2-(benzenesulfonyl)-5-methoxy-4-phenylmethoxyphenyl]-2-(4-carbamimidoylanilino)acetyl]amino]-2-phenylacetic acid family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00384857 Functional Category Bioactive
Superfamily Coagulation factor VII and Trypsin-1 Binder Superfamily
Class Class 4605

Cousin Family NamesSeedsMembers
Coagulation factor VII and Coagulation factor X Inhibitor 4-(4... 2 12
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Coagulation factor VII and Prothrombin inhibitor (S)-[(R)-2-(4... 2 8
Coagulation factor X inhibitor (Z)-3-[5-carbamimidoyl-2-(2-met... 2 0
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752KC... 3 3
Coagulation factor VII and Tissue factor inhibitor phenylglyci... 4 27
Coagulation factor VII and Prothrombin inhibitor SureCN231899 ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00384852 CHEMBL2431588 Bioactive N-(benzenesulfonyl)-2-(4-carbamimidoylanilino)-2-(3-ethoxy-4-propan-2-yloxyphenyl)acetamide
CFAMM00384857 CHEMBL178134 Bioactive (2S)-2-[[(2R)-2-[2-(benzenesulfonyl)-5-methoxy-4-phenylmethoxyphenyl]-2-(4-carbamimidoylanilino)acetyl]amino]-2-phenylacetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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