CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8036
Family Name C-C chemokine receptor type 2 and Potassium voltage-gated channel subfamily H member 2 ligand [(1S,3R)-3-[[(4S)-3-ethyloxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00384985 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 2
Class Class 1006

Cousin Family NamesSeedsMembers
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
JAK Inhibitor Momelotinib Family 33 83
Class II cytokine receptor Ligand IL-10 Family 7 45
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Calcitonin gene-related peptide type 1 receptor Ligand Isomer ... 30 31
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 f... 9 5
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 5 20
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
C-C chemokine receptor type 1 ligand [(1S)-3-[[(3S,4S)-3-metho... 1 15
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 7 6
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 0
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 0
Transient receptor potential cation channel subfamily V member... 1 0
Cannabinoid receptor 2 ligand AGN-PC-07CRHA family 4 8
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00384986 CHEMBL1782376 Bioactive SureCN3025574
CFAMM00384985 CHEMBL1782578 Bioactive [(1S,3R)-3-[[(4S)-3-ethyloxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
CFAMM00384987 CHEMBL1782375 Bioactive [(1S,3R)-3-(3,3a,4,6,7,7a-hexahydro-2H-pyrano[4,3-b]pyrrol-1-yl)-1-propan-2-ylcyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26857 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543