CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8052
Family Name Renin inhibitor SureCN1865980 family
No. of Seeds 9 No. of Other Members 4
Family Centroid CFAMM00385052 Functional Category Bioactive
Superfamily Renin and Nociceptin receptor Binder Superfamily
Class Class 3243

Cousin Family NamesSeedsMembers
Delta-type opioid receptor Ligand Loperamide Family 8 55
VTP-27999 family 24 23
C-C chemokine receptor type 1 ligand SureCN7463390 family 1 6
Renin inhibitor (3R)-3-[(1S)-1-hydroxy-5-methoxy-1-(2-phenoxyp... 1 7
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 1
C-C chemokine receptor type 1 ligand N-[(2R)-1-[(4S)-4-(4-chlo... 15 6
C-C chemokine receptor type 1 ligand 4-chloro-N-[(2R)-1-[(4S)-... 6 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[(4S)-4-(4-chlo... 1 0
Renin inhibitor SureCN1858210 family 9 0


External ID

Functional Category

Molecule Name

CFAMM00385052 CHEMBL1783183 Bioactive SureCN1865980
CFAMM00385058 CHEMBL496042 Bioactive SureCN1864572
CFAMM00385051 CHEMBL496821 Bioactive SureCN1862927
CFAMM00385056 CHEMBL497420 Bioactive SureCN1859649
CFAMM00385049 CHEMBL496430 Bioactive SureCN1863906
CFAMM00385055 CHEMBL604248 Bioactive SureCN1861802
CFAMM00385061 CHEMBL484897 Bioactive SureCN1862902
CFAMM00385054 CHEMBL589399 Bioactive SureCN1860577
CFAMM00385059 CHEMBL2024249 Bioactive (3R)-N-[(2S)-2-amino-3-cyclohexylpropyl]-3-[(1S)-1-(3-chloro-2-fluorophenyl)-1-hydroxy-5-methoxypentyl]piperidine-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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