CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8055
Family Name Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-aminobutyric acid receptor subunit beta-3 ligand 4-amino-8-(2,6-dimethylphenyl)-N-propylcinnoline-3-carboxamide family
No. of Seeds 8 No. of Other Members 1
Family Centroid CFAMM00385078 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-aminobutyric acid receptor subunit beta-3 ligand 4-amino-8-(2,6-dimethylphenyl)-N-propylcinnoline-3-carboxamide Superfamily
Class Class 1644

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M8RE fa... 6 1
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 2 3
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 1
Leucine-rich repeat serine/threonine-protein kinase 2 and Macr... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385073 CHEMBL1783246 Bioactive 4-amino-8-phenyl-N-propylcinnoline-3-carboxamide
CFAMM00385072 CHEMBL1783247 Bioactive 4-amino-8-(2,5-dimethylphenyl)-N-propylcinnoline-3-carboxamide
CFAMM00385078 CHEMBL1783248 Bioactive 4-amino-8-(2,6-dimethylphenyl)-N-propylcinnoline-3-carboxamide
CFAMM00385071 CHEMBL1783245 Bioactive 4-amino-8-(2-methylpropyl)-N-propylcinnoline-3-carboxamide
CFAMM00385077 CHEMBL1783249 Bioactive 4-amino-8-(3-methylphenyl)-N-propylcinnoline-3-carboxamide
CFAMM00385076 CHEMBL1783251 Bioactive 4-amino-8-(2,4-dimethylphenyl)-N-propylcinnoline-3-carboxamide
CFAMM00385075 CHEMBL1783250 Bioactive 4-amino-8-(2-methylphenyl)-N-propylcinnoline-3-carboxamide
CFAMM00385074 CHEMBL1783252 Bioactive 4-amino-8-(3,5-dimethylphenyl)-N-propylcinnoline-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27273 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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