CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8056
Family Name Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-aminobutyric acid receptor subunit beta-3 ligand 4-amino-8-(2,5-dimethoxyphenyl)-7-fluoro-N-propylcinnoline-3-carboxamide family
No. of Seeds 8 No. of Other Members 12
Family Centroid CFAMM00385088 Functional Category Bioactive
Superfamily Coagulation factor X Inhibitor Apixaban Superfamily
Class Class 999

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 5
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0


External ID

Functional Category

Molecule Name

CFAMM00385087 CHEMBL1783271 Bioactive 4-amino-N-cyclopropyl-8-(2,5-dimethoxyphenyl)-7-fluorocinnoline-3-carboxamide
CFAMM00385088 CHEMBL1783272 Bioactive 4-amino-8-(2,5-dimethoxyphenyl)-7-fluoro-N-propylcinnoline-3-carboxamide
CFAMM00385094 CHEMBL1783253 Bioactive 4-amino-N-cyclopropyl-8-(2,5-dimethoxyphenyl)cinnoline-3-carboxamide
CFAMM00385079 CHEMBL1783281 Bioactive 4-amino-8-(2-methoxy-5-methylphenyl)-N-propylcinnoline-3-carboxamide
CFAMM00385084 CHEMBL1783274 Bioactive 4-amino-8-(2,5-dimethoxyphenyl)-N-ethyl-7-fluorocinnoline-3-carboxamide
CFAMM00385082 CHEMBL1783282 Bioactive 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
CFAMM00385081 CHEMBL1783283 Bioactive 4-amino-8-(2,4-dimethoxyphenyl)-7-fluoro-N-propylcinnoline-3-carboxamide
CFAMM00385089 CHEMBL1783273 Bioactive 4-amino-N-cyclobutyl-8-(2,5-dimethoxyphenyl)-7-fluorocinnoline-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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