CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM806
Family Name Epidermal growth factor receptor ligand AGN-PC-07Q1HU family
No. of Seeds 4 No. of Other Members 17
Family Centroid CFAMM00316104 Functional Category Bioactive with Natural Product
Superfamily Gamma-aminobutyric acid A receptor Ligand Bromazepam Superfamily
Class Class 553

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Prothrombin Inhibitor Ximelegatran Family 8 157
Transient receptor potential cation channel subfamily V member... 15 158
Neuromedin-K receptor Ligand SB222200 Family 17 235
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Family 6 29
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Lethal factor Inhibitor N,n'-bis(4-amino-2-methylquinolin-6-yl... 2 11
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Poly [ADP-ribose] polymerase 1 Inhibitor 3-ethenylquinoline-8-... 8 4
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Metabotropic glutamate receptor 1 Ligand N-(2-phenylpropyl)qui... 3 1
Metabotropic glutamate receptor 1 Ligand (e)-4,4-dimethyl-1-qu... 2 2
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 3 1
Epidermal growth factor receptor ligand (2R,3R)-3-[[4-(3-bromo... 3 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 0
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Melanin-concentrating hormone receptor 1 ligand SureCN6198980 ... 13 0
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 3 2
Epidermal growth factor receptor ligand AGN-PC-078X7L family 4 0
Epidermal growth factor receptor ligand (E)-N-[4-(3-bromoanili... 2 1
Epidermal growth factor receptor ligand N-[4-(3-bromoanilino)-... 2 0
Telomerase reverse transcriptase inhibitor N-[9-(4-aminoanilin... 1 11
Melanin-concentrating hormone receptor 1 ligand SureCN6200892 ... 1 0
Epidermal growth factor receptor ligand (E)-1-[4-(3-bromoanili... 9 0
Epidermal growth factor receptor ligand AGN-PC-078X9P family 4 0
Epidermal growth factor receptor ligand AGN-PC-03PBNC family 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00316104 CHEMBL1090840 Bioactive AGN-PC-07Q1HU
CFAMM00316097 CHEMBL217845 Bioactive SureCN6204055
CFAMM00316093 CHEMBL281300 Bioactive SureCN6382090
CFAMM00316111 CHEMBL1089524 Bioactive AGN-PC-07Q1KS

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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