CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8070
Family Name Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5 ligand 9-(dimethylamino)-3-(4-methylphenyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one family
No. of Seeds 13 No. of Other Members 37
Family Centroid CFAMM00317264 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5 Binder Superfamily
Class Class 3795

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
Transient receptor potential cation channel subfamily V member... 1 17
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Muscarinic acetylcholine receptor M4 Ligand VU10007 Family 2 17
Deoxycytidine kinase inhibitor N-[(1S,3S)-3-(4-amino-5-fluoro-... 2 5
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 12
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Metabotropic glutamate receptor 1 ligand AGN-PC-046KML family 7 40
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9TG5 family 11 10
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9S6C family 10 1
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9PTC family 4 1
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9T4A family 3 0
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9T4C family 1 0
Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2... 2 3
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 7 1
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Metabotropic glutamate receptor 1 ligand SureCN8238697 family 2 0
Metabotropic glutamate receptor 1 ligand SureCN8238239 family 3 0
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 5 0
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385252 CHEMBL225032 Bioactive SureCN8241765
CFAMM00385244 CHEMBL224617 Bioactive AGN-PC-00CLEP
CFAMM00385243 CHEMBL1783875 Bioactive AGN-PC-046KIK
CFAMM00385233 CHEMBL1783863 Bioactive AGN-PC-0A9TG4
CFAMM00385241 CHEMBL386565 Bioactive A 841720

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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