CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8071
Family Name Metabotropic glutamate receptor 1 ligand AGN-PC-0A9TG5 family
No. of Seeds 11 No. of Other Members 10
Family Centroid CFAMM00385234 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 1 and DNA polymerase beta Binder Superfamily
Class Class 718

Cousin Family NamesSeedsMembers
Abelson tyrosine-protein kinase 2 inhibitor thiazole derivativ... 19 50
Transient receptor potential cation channel subfamily V member... 1 17
Muscarinic acetylcholine receptor M4 Ligand VU10007 Family 2 17
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
Coagulation factor X inhibitor AGN-PC-078Y4E family 4 6
Metabotropic glutamate receptor 1 ligand AGN-PC-046KML family 7 40
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 13 37
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9S6C family 10 1
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9PTC family 4 1
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9T4A family 3 0
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9T4C family 1 0
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 4 10
Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2... 2 3
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 2 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 7 1
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00JFFW ... 12 14
Melanin-concentrating hormone receptor 1 ligand 6-(4-chlorophe... 2 0
Histone deacetylase 1 inhibitor 5-[5-[[(2-chlorophenyl)methyla... 4 1
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Metabotropic glutamate receptor 1 ligand SureCN8238697 family 2 0
Metabotropic glutamate receptor 1 ligand SureCN8238239 family 3 0
Gamma-aminobutyric acid receptor subunit alpha-2 and Gamma-ami... 6 4
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00JGEQ ... 1 1
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 1 4
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 1
High affinity nerve growth factor receptor ligand isothiazole,... 4 3
Muscarinic acetylcholine receptor M4 ligand 3-amino-5-chloro-4... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385277 CHEMBL1951879 Bioactive CHEMBL1951879
CFAMM00385276 CHEMBL1783864 Bioactive AGN-PC-046KKR
CFAMM00385274 CHEMBL1951661 Bioactive CHEMBL1951661
CFAMM00385280 CHEMBL1783874 Bioactive AGN-PC-046KIM
CFAMM00385279 CHEMBL241547 Bioactive SureCN8244782
CFAMM00385285 CHEMBL1951880 Bioactive CHEMBL1951880

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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