CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8081
Family Name Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5 ligand CHEMBL2205909 family
No. of Seeds 11 No. of Other Members 7
Family Centroid CFAMM00385359 Functional Category Bioactive
Superfamily Beta-lactamase and Caspase-7 Binder Superfamily
Class Class 3402

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
Vascular endothelial growth factor receptor 2 ligand ST5005116... 1 11
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 0
Inositol monophosphatase 1 and Microtubule-associated protein ... 1 12
Metabotropic glutamate receptor 1 ligand AGN-PC-046KML family 7 40
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 14
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 6 5
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 1
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 1 1
Metabotropic glutamate receptor 1 ligand SureCN8238253 family 9 0


External ID

Functional Category

Molecule Name

CFAMM00385364 CHEMBL2205378 Bioactive CHEMBL2205378
CFAMM00385371 CHEMBL2205914 Bioactive CHEMBL2205914
CFAMM00385370 CHEMBL2205917 Bioactive CHEMBL2205917
CFAMM00385362 CHEMBL2203308 Bioactive CHEMBL2203308
CFAMM00385368 CHEMBL1784056 Bioactive AGN-PC-0A9RTZ
CFAMM00385359 CHEMBL2205909 Bioactive CHEMBL2205909
CFAMM00385358 CHEMBL2205908 Bioactive CHEMBL2205908

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



59437 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543