CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8085
Family Name Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-3-fluoro-4-methyl-5-[4-[(2-methyl-1,3-thiazol-4-yl)methylcarbamoyl]phenyl]benzamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00385378 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 5 Ligand 3-[(2-methyl-4-thiazolyl)ethynyl]benzamide Superfamily
Class Class 2283

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3


External ID

Functional Category

Molecule Name

CFAMM00385380 CHEMBL595019 Bioactive CHEMBL595019
CFAMM00385378 CHEMBL1784169 Bioactive N-cyclopropyl-3-fluoro-4-methyl-5-[4-[(2-methyl-1,3-thiazol-4-yl)methylcarbamoyl]phenyl]benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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