CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8087
Family Name Pol polyprotein and Pepsin A-5 inhibitor Lysine derivative 28 family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00385392 Functional Category Bioactive
Superfamily Pol polyprotein and Pepsin A-5 Binder Superfamily
Class Class 4613

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Amprenavir Family 7 15
Pol polyprotein inhibitor Lysine Sulfonamide 11o family 2 6
Pol polyprotein inhibitor Lysine Sulfonamide 14a family 12 3
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 0
Pol polyprotein inhibitor AC1LAHQ3 family 13 0
Pol polyprotein inhibitor Lysine derivative 12 family 6 6
Neurotensin receptor type 1 and Retinal dehydrogenase 1 ligand... 1 19


External ID

Functional Category

Molecule Name

CFAMM00385392 CHEMBL178421 Bioactive Lysine derivative 28
CFAMM00385384 CHEMBL181767 Bioactive Lysine derivative 27

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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