CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8112
Family Name Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor AGN-PC-075CLH family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00385585 Functional Category Bioactive
Superfamily SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand Glimepiride Superfamily
Class Class 109

Cousin Family NamesSeedsMembers
SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand T... 3 35
Cathepsin K Inhibitor Odanacatib Family 33 84
Thymidylate synthase Inhibitor N-[tosyl-d-prolinyl]amino-ethan... 1 10
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-acet... 6 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-valp... 8 5
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Disintegrin and metalloproteinase domain-containing protein 17... 6 5
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[2-[... 10 5
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor (3R)-3-... 3 2
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 6 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[car... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385581 CHEMBL178560 Bioactive AGN-PC-075CL4
CFAMM00385585 CHEMBL181082 Bioactive AGN-PC-075CLH
CFAMM00385584 CHEMBL181422 Bioactive AGN-PC-075CMJ
CFAMM00385583 CHEMBL180506 Bioactive AGN-PC-075CM8
CFAMM00385582 CHEMBL180936 Bioactive AGN-PC-075CLM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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