CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8115
Family Name Coagulation factor VII and Prothrombin inhibitor (S)-[(R)-2-(4-Benzyloxy-3-Methoxy-Phenyl)-2-(4-Carbamimidoyl-Phenylamino)-Acetylamino]-Phenyl-Acetic Acid family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00306796 Functional Category Bioactive
Superfamily Coagulation factor VII and Trypsin-1 Binder Superfamily
Class Class 4605

Cousin Family NamesSeedsMembers
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Coagulation factor VII and Coagulation factor X Inhibitor 4-(4... 2 12
Multidrug resistance protein 1 and Multidrug resistance-associ... 3 55
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Coagulation factor VII and Trypsin-1 inhibitor (2S)-2-[[(2R)-2... 2 5
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-(1,3-ben... 5 0
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752KC... 3 3
Coagulation factor VII and Tissue factor inhibitor phenylglyci... 4 27
Coagulation factor VII and Prothrombin inhibitor SureCN231899 ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00385625 CHEMBL366921 Bioactive (2S)-2-[[(2R)-2-(4-carbamimidoylanilino)-2-[5-methoxy-2-(2-phenylacetyl)-4-phenylmethoxyphenyl]acetyl]amino]-2-phenylacetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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