CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8116
Family Name Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benzodipyrazole deriv. 7j family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00385634 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase PLK4 and cAMP Binder Superfamily
Class Class 842

Cousin Family NamesSeedsMembers
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 1 4
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor SBC family 5 18
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 3 5
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-075CD... 2 8
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 3
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
cAMP-dependent protein kinase catalytic subunit PRKX and Rho-a... 1 1
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Serine/threonine-protein kinase PLK4 inhibitor (3E)-5-methoxy-... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385634 CHEMBL178629 Bioactive dihydro-benzodipyrazole deriv. 7j

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26817 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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