CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8117
Family Name Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-3 beta inhibitor CHEMBL180779 family
No. of Seeds 11 No. of Other Members 11
Family Centroid CFAMM00385644 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 2498

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Histamine H3 receptor ligand SureCN2784306 family 5 3
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 7 1
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 0
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 3 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Mu-type opioid receptor and Mu-type opioid receptor ligand (3S... 6 2
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 4 4
Cannabinoid receptor 1 ligand (4-hydroxynaphthalen-1-yl)-[1-(2... 2 0
Glycogen synthase kinase-3 beta inhibitor bip-135 family 3 1
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 6 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385647 CHEMBL2386091 Bioactive CHEMBL2386091
CFAMM00385646 CHEMBL2386090 Bioactive CHEMBL2386090
CFAMM00385645 CHEMBL181518 Bioactive AGN-PC-075C5M
CFAMM00385644 CHEMBL180779 Bioactive CHEMBL180779
CFAMM00385657 CHEMBL181371 Bioactive AGN-PC-075C7Y
CFAMM00385637 CHEMBL361635 Bioactive AGN-PC-075C5W
CFAMM00385650 CHEMBL2386094 Bioactive CHEMBL2386094
CFAMM00385643 CHEMBL178646 Bioactive AGN-PC-075C6S
CFAMM00385649 CHEMBL2386093 Bioactive CHEMBL2386093
CFAMM00385642 CHEMBL178766 Bioactive AGN-PC-075C6G
CFAMM00385648 CHEMBL2386092 Bioactive CHEMBL2386092

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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