CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8122
Family Name Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor SBC family
No. of Seeds 5 No. of Other Members 18
Family Centroid CFAMM00385709 Functional Category Bioactive
Superfamily Cyclin-A2 and Cyclin-dependent kinase 2 Binder Superfamily 3
Class Class 1276

Cousin Family NamesSeedsMembers
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 1 4
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 1 7
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 3 5
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-075CD... 2 8
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 3
Rho-associated protein kinase 2 and Rho-associated protein kin... 2 6
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
cAMP-dependent protein kinase catalytic subunit PRKX and Rho-a... 1 1
Hepatocyte growth factor receptor ligand 5-(3-methyl-1,2-thiaz... 5 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 1
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385709 CHEMBL360520 Bioactive SBC
CFAMM00385701 CHEMBL361862 Bioactive 2bkz
CFAMM00385704 CHEMBL361595 Bioactive dihydro-benzodipyrazole deriv. 7f
CFAMM00385710 CHEMBL178750 Bioactive dihydro-benzodipyrazole deriv. 7c
CFAMM00385703 CHEMBL181616 Bioactive dihydro-benzodipyrazole deriv. 7d

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26854 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543